Colic Relief Plus® by Second to Mom

(90 customer reviews)
(90 customer reviews)




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Reduces crying time by 60% in as little as 7 days.*


Allergen-free, non-GMO and vegan-friendly.

Easy to Use

The bottle-connected dropper regulates how much is administered.


4 out of 5 families reported significant reduction in colic-related symptoms.

Calm Your Baby From the Inside Out

Second to Mom’s Colic Relief Plus® is a clinically-validated, patented infant probiotic supplement formulated to help relieve the symptoms of colic. We use a specific strain that supports healthier microflora balance, which is correlated with decreased crying time in colicky infants.

Chrissy Arsenault

“To moms and families: I know you’re doing your best. You’re not alone on this journey. If you’re looking for a quick but lasting solution that is most compatible with your baby’s gut, talk to your pediatrician or Registered Dietitian about Colic Relief Plus®.”
Read Full Testimony

How to Use Colic Relief Plus®

Easy to use with super clear instructions, you just administer 5 drops on it’s own or add to one bottle of formula or breast milk every day. The product comes with a cleanable, handy container and sanitary dropper that won’t get moldy.

It takes about 7 days to start seeing results, and it is recommended to continue use for 3 months for best results. There is no harm in continuing longer though, and some parents see benefits for up to one year. Watch Our Instructional Video

Supplement Facts

Serving Size
5 Drops (Daily)
Servings Per Container
About 32
Floradapt™ Baby Colic probiotic blend
8.33mg* (%DV)
Providing 1 Billion CFU
P.pentosaceus KABP™-041
B.longum KABP™-042

*Daily Value (DV) not established

Safe for All + Extra Benefits

  • Documented Active ingredients that are active for your baby. 
  • GMO-Free ingredients sourced through hand-picked providers.
  • Vegan-Friendly thanks to an entirely plant-based ingredient list.
  • Patented Product ensures safety-related best practices were followed.
  • Feeding-Flexibility for breast-fed or formula-fed babies.
  • Gas-Free unlike some other probiotic drops.

* According to recent study for crying time claims

Frequently Asked Questions

In clinical trials Colic Relief Plus® showed a significant reduction, 60%, in crying time as early as 7 days after starting continuous use.

Colic can persist up until 12 months. We recommend continuous daily use starting as early as 2 weeks old through 12 months of age. Depending on the severity and length of your colic or colic like symptoms, you can safely use as long as needed.

Absolutely. It is a patented product. This classification ensures the correct steps were taken to safely provide a product to babies.

We recommend continuous daily use starting as early as 2 weeks old through 12 months of age.

For the full list, please visit our Frequently Asked Questions page.

Questions About Our Products?

Our team is available for support. Get in touch with us to find out if Colic Relief Plus® is right for your baby.

Customer Reviews

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katie w
Your Rating :

Thanks to the Stellar Product Testing Panel for providing me with this colic drops. I was almost at my wits end with my colicky baby. Then this little bottle of heaven arrived in my mailbox. I started them almost immediately. Within the first week I noticed my son crying less, not as gassy, and his constipation was decreased. We use these drops every morning in our first bottle of formula. I warm up his formula and add the drops to his bottle and invert it a couple times to mix. These drops are super user friendly the dropper is easy to get drops out. I will be continuing them from now on!

Your Rating :

What a relief! My baby had colic and these drops were a miracle worker. They are clinically validated so we didn’t have a problem giving them to our baby. We also like that they have the added health benefit of being a probiotic, and that it is fast-acting. Each day we saw an improvement with her crying and fussiness, and now it is almost non-existent. You just add a few drops in her bottle and let the magic work. All around she has become a much happier baby and we are much happier parents. Thanks to the Stellar Product Testing Panel for providing me with these colic drops.

Your Rating :

I was very surprised with these drops. My baby has been having super bad gas since the beginning. We have tried several bottles and several formulas but she has always had bad gas and been super irritable when so. We have tried gas drops but it didn’t always work. I was so thankful to have these drops eligible to review as a part of the Stellar Product Testing Panel. For starters, the box itself gives me hope due to the fact it is so aesthetically appealing. I see a loving mother and a calm and settled baby. It makes me want to buy it based on what I see. I love the fact that it is all natural product and is GMO free and Vegan friendly, it makes me know that what I’m giving my baby is okay and not full of chemicals. It helped reduce my child’s crying time and uneasiness by the 7th day . I noticed that she was almost completely rid of her excessive gas and would recommend these over gas drops. The added probiotics give me reassurance knowing she’s got healthy gut bacteria in there now to help balance out everything. I gave this to my baby through the dropper since it was easier for me to know she essentially got all of the drops. If I put it in the bottle, sometimes she wouldn’t eat all of it and I felt like I was wasting product. She took it very well and swallowed it like she would’ve swallowed her formula. I honestly didn’t have any issues with this product at all and would continue to use it for my child. It’s a well rounded product and that it is natural would push anyone to want the product more. Once again, I am beyond thankful for this product from the Stellar Product Testing Panel!

Nurse Mommy
Your Rating :

Just 5 drops a day and viola, happy baby! I had tried literally everything to soothe my newborn and nothing worked. When finally I tried these for free in exchange for a review with the Stellar Testing Panel. Within a few days, baby was resting peacefully. I just drop these into his mouth right before nursing and I have no issues. It’s very easy to administer, and baby has no issues taking it. I love the benefits of being a probiotic as well, which means it helps with digesting foods and a healthy tummy! 

Your Rating :

I started these probiotics when my little guy was 13 weeks old, he’s 15 weeks now. He is EBF and is a “happy spitter”, spitting up a lot after each meal. He also struggles with gas, causing him pain. I haven’t been able to identify anything in my diet that makes things better or worse so I thought I’d try these drops. He takes 5 drops/day that I put on his pacifier. I do like the silicone dropper, much easier to strategically place the drops around the paci. I really appreciate the ingredients and transparency of the Second to Mom company. We have been using them for nearly 2 weeks now and I haven’t noticed a difference. I’d like to give it some more time and will update my review.
I received this props if as part of the Stellar Product Testing Panel.

Haley Hall
Your Rating :

I received the Colic Relief Plus drops to try and review by the Stellar Product Testing Panel. I think that these drops are a good probiotic and am pleased with the ingredients; however, I am not sure that they made much of a difference with my daughters colic. We administered the drops directly (not through her bottle) and they were easy to give. Colic is so draining and we, like many other parents, were willing to try almost anything to help with our daughters discomfort and crying. I think this could be a good tool for other parents to try for their baby’s colic, but I don’t think they made a difference for us. Overall we could live without these, but I will continue to use them until they are gone.

Erica Eberly
Your Rating :

I received the Colic Relief Plus drops and can not recommend these enough! I received these colic drops from the Stellar Product Testing Panel and what a difference i have seen in her overall comfort!
On a scale of 1 to 5, I would say my 2 month old is in the 3 range of fussiness. Before using these drops she was extremely gassy, and spit up quite a bit. I started using these drops the day they arrived and by about day 4 I noticed a difference. Her cry time decreased significantly and she was not nearly as gassy and just happier and more pleasant in general.
I found these drops to be super easy to administer as the dropper that you use is very accurate and slow. My little one does not use a bottle daily so I would place 5 drops on her binky so that I could easily tell how much she was getting each time.
I would recommend these drops to anyone that has even a slightly fussy baby. The probiotics worked wonders with my baby, and it does not hurt to give it a try!

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